Labels:text | screenshot | black and white | black | font | document OCR: the type The most common group of disorders o his results are due to C21- hydroxylase deficiency. T an increasein an inability to produce cortisol and ir rtical in ACTH levels, which leads to adrenoc of hyperplasia and to excessive production androgens. external This in turn results in virilisation of the ious genitalia in the female foetus, and preco ciency pseudopuberty in male infants. If the de extends to the zona glomerulosa P450 C2 i salt loss deficiency of aldosterone production wit cortical will also occur. This can result in adreno life. In thisdeficiency or crisis, neonatally or later in nzyme is disorder, the substrate for the defective e d synthesis17-hydroxyprogesterone (see Fig. 7.12), a increase, of this steroid, and its plasma levels, wil
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